Excited to welcome Dr. Matthew Pagano to PentaHealth Internal Medicine West Chester! He started on August 1st, 2025, and is accepting new patients.
Matthew Pagano, DO received his undergraduate degree from Penn State before earning his Doctorate of Osteopathic Medicine at the Philadelphia College of Osteopathic Medicine. Following the completion of his residency at United Memorial Medical Center/Rochester Regional Health in Batavia, NY, he stayed on at the hospital during the pandemic, serving as both a clinical physician and a member of the teaching faculty. In practice, Dr. Pagano provides comprehensive medical services. He is skilled at performing routine procedures such as biopsies and injections and offers Osteopathic Manipulative Treatment for various conditions, including musculoskeletal pain, constipation, and headaches.
Dr. Pagano is a dedicated Family Medicine Physician (currently only seeing adults 18 years or older) who believes health is more than just a list of symptoms or the data in a medical file. He is passionate about helping patients feel seen and heard as well as helping patients understand their health and feel involved in their care.
In his free time, Dr. Pagano enjoys visiting Longwood Gardens, reading speculative fiction, and spending time with his wife and their two tuxedo cats.

